Pablo Umaña: search on Z-Library

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1

Engineering therapeutic bispecific antibodies using CrossMab technology

Klein, Christian, Schaefer, Wolfgang, Regula, Joerg T., Dumontet, Charles, Brinkmann, Ulrich, Bacac, Marina, Umaña, Pablo

Journal:

Year:

2018

Language:

english

File:

PDF, 797 KB

english, 2018

2

Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co-expression of heterologous β1, 4-N-acetylglucosaminyltransferase III and Golgi α-mannosidase II

Claudia Ferrara, Peter Brünker, Tobias Suter, Samuel Moser, Ursula Püntener, Pablo Umaña

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 340 KB

english, 2006

3

Application of a MABEL Approach for a T-Cell-Bispecific Monoclonal Antibody

Dudal, Sherri, Hinton, Heather, Giusti, Anna M., Bacac, Marina, Muller, Magali, Fauti, Tanja, Colombetti, Sara, Heckel, Tobias, Giroud, Nicolas, Klein, Christian, Umaña, Pablo, Benincosa, Lisa, Bachl,

Journal:

Journal of Immunotherapy

Year:

2016

Language:

english

File:

PDF, 520 KB

english, 2016

4

Antitumour activity of the glycoengineered type II anti-CD20 antibody obinutuzumab (GA101) in combination with the MDM2 selective antagonist idasanutlin (RG7388)

Herting, Frank, Herter, Sylvia, Friess, Thomas, Muth, Gunther, Bacac, Marina, Sulcova, Jitka, Umana, Pablo, Dangl, Markus, Klein, Christian

Journal:

European Journal of Haematology

Year:

2016

Language:

english

File:

PDF, 874 KB

english, 2016

5

A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease

Peterson, Laurence B., Bell, Charles J.M., Howlett, Sarah K., Pekalski, Marcin L., Brady, Kevin, Hinton, Heather, Sauter, Denise, Todd, John A., Umana, Pablo, Ast, Oliver, Waldhauer, Inja, Freimoser-G

Journal:

Journal of Autoimmunity

Year:

2018

Language:

english

File:

PDF, 2.77 MB

english, 2018

6

FcγRIIIa chromatography to enrich a-fucosylated glycoforms and assess the potency of glycoengineered therapeutic antibodies

Freimoser–Grundschober, Anne, Rueger, Petra, Fingas, Felix, Sondermann, Peter, Herter, Sylvia, Schlothauer, Tilman, Umana, Pablo, Neumann, Christiane

Journal:

Journal of Chromatography A

Year:

2019

Language:

english

File:

PDF, 875 KB

english, 2019

7

A mathematical model of N-linked glycoform biosynthesis

Pablo Umaña, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1997

Language:

english

File:

PDF, 319 KB

english, 1997

8

Response to: Monoclonal antibodies targeting CD20

Klein, Christian, Lammens, Alfred, Schäfer, Wolfgang, Georges, Guy, Schwaiger, Manfred, Mössner, Ekkehard, Hopfner, Karl-Peter, Umaña, Pablo, Niederfellner, Gerhard

Journal:

Year:

2013

Language:

english

File:

PDF, 266 KB

english, 2013

9

Tetracycline-Regulated overexpression of glycosyltransferases in Chinese hamster ovary cells

Pablo Umaña, Joël Jean-Mairet, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 379 KB

english, 1999

10

CEA TCB: A novel head-to-tail 2:1 T cell bispecific antibody for treatment of CEA-positive solid tumors

Bacac, Marina, Klein, Christian, Umana, Pablo

Journal:

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

11

Combination therapy with the type II anti-CD20 antibody obinutuzumab

Klein, Christian, Bacac, Marina, Umana, Pablo, Fingerle-Rowson, Günter

Journal:

Expert Opinion on Investigational Drugs

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

12

T Cell-Engaging Therapy for Solid Tumors

de Miguel, Maria, Umana, Pablo, Gomes de Morais, Ana Luiza, Moreno, Victor, Calvo, Emiliano

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 1.53 MB

2020

13

Enhanced anti-tumor activity of the glycoengineered type II CD20 antibody obinutuzumab (GA101) in combination with chemotherapy in xenograft models of human lymphoma

Herting, Frank, Friess, Thomas, Bader, Sabine, Muth, Gunter, Hölzlwimmer, Gabriele, Rieder, Natascha, Umana, Pablo, Klein, Christian

Journal:

Leukemia and Lymphoma

Year:

2014

Language:

english

File:

PDF, 2.21 MB

english, 2014

14

Drivers of biomass stocks in Northwestern South American forests: Contributing new information on the Neotropics

Aldana, Ana M., Villanueva, Boris, Cano, Ángela, Correa, Diego F., Umaña, María Natalia, Casas, Luisa Fernanda, Cárdenas, Sasha, Henao-Diaz, Luis Francisco, Stevenson, Pablo R.

Journal:

Forest Ecology and Management

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

15

10.1038/89349

Umaña, Pablo, Gerdes, Christian A., Stone, Daniel, Davis, Julian R.E., Ward, Daniel, Castro, Maria G., Lowenstein, Pedro R.

Journal:

Nature Biotechnology

Year:

2001

Language:

english

File:

PDF, 1.52 MB

english, 2001

16

Chemotherapy-free, triple combination of obinutuzumab, venetoclax and idasanutlin: antitumor activity in xenograft models of non-Hodgkin lymphoma

Herting, Frank, Friess, Thomas, Umaña, Pablo, Middleton, Steven, Klein, Christian

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 824 KB

english, 2017

17

P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation

Darowski, Diana, Jost, Christian, Stubenrauch, Kay, Wessels, Uwe, Benz, Jörg, Ehler, Andreas, Freimoser-Grundschober, Anne, Brünker, Peter, Mössner, Ekkehard, Umaña, Pablo, Kobold, Sebastian, Klein, C

Journal:

Protein Engineering Design and Selection

Year:

2019

Language:

english

File:

PDF, 2.25 MB

english, 2019

18

GA101 P329G LALA, a variant of obinutuzumab with abolished ADCC, ADCP and CDC function but retained cell death induction, is as efficient as rituximab in B cell depletion and antitumor activity

Herter, Sylvia, Herting, Frank, Muth, Gunter, van Puijenbroek, Erwin, Schlothauer, Tilman, Ferrara, Claudia, Brady, Kevin, Lang, Sabine, Bacac, Marina, Mössner, Ekkehard, Umana, Pablo, Klein, Christia

Journal:

Year:

2017

Language:

english

File:

PDF, 915 KB

english, 2017

19

The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo

Palazzo, Adam, Herter, Sylvia, Grosmaire, Laura, Jones, Randy, Frey, Christian R., Limani, Florian, Bacac, Marina, Umana, Pablo, Oldham, Robert J., Marshall, Michael J. E., Cox, Kerry L., Turaj, Anna

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

20

10.1038/6179

Bailey, James E., Umaña, Pablo, Jean–Mairet, Joël, Moudry, Radmila, Amstutz, Hanspeter

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 136 KB

english, 1999

21

TCT-888 Patients With Aortic Stenosis Referred For Transcatheter Aortic Valve Implantation: Treatment Decision, In-hospital Outcome And Determinants Of Survival

Rutger-Jan Nuis, Antonio Dager, Robert M.A. Van Der Boon, Marisol Jaimes, Bernardo Caicedo, Jaimes Fonseca, Nicolas van Mieghem, Luis Benitez, Juan Pablo Umana, William O'Neill, Eduardo de Marchena, P

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 163 KB

english, 2012

22

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Claudia Ferrara, Sandra Grau, Christiane Jäger, Peter Sondermann, Peter Brünker, Inja Waldhauer, Michael Hennig, Armin Ruf, Arne Christian Rufer, Martine Stihle, Pablo Umaña and Jörg Benz

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

23

Improved Effector Functions of a Therapeutic Monoclonal Lewis Y-Specific Antibody by Glycoform Engineering

Schuster, Manfred, Umana, Pablo, Ferrara, Claudia, Brünker, Peter, Gerdes, Christian, Waxenecker, Günter, Wiederkum, Susanne, Schwager, Cornelia, Loibner, Hans, Himmler, Gottfried, Mudde, Geert C.

Journal:

Cancer Research

Year:

2005

Language:

english

File:

PDF, 581 KB

english, 2005

24

Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

Schlothauer, Tilman, Herter, Sylvia, Koller, Claudia Ferrara, Grau-Richards, Sandra, Steinhart, Virginie, Spick, Christian, Kubbies, Manfred, Klein, Christian, Umaña, Pablo, Mössner, Ekkehard

Journal:

Protein Engineering Design and Selection

Year:

2016

Language:

english

File:

PDF, 881 KB

english, 2016

25

Improved Lytic Potential of a Therapeutic Monoclonal Antibody by Glycoform Engineering

Schuster, Manfred, Umana, Pablo, Mudde, Geert C, Himmler, Gottfried, Loibner, Hans

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 58 KB

english, 2004

26

Fibroelastoma papilar incidental o sintomático ¿Debe intervenirse?

Guerrero, Albert F., Camacho, Jaime, Umaña Mallarino, Juan Pablo, Tavera, Andrea, Niño Monsalve, Jorge Fabián, Carreño, Marisol

Journal:

Revista Colombiana de Cardiología

Year:

2017

File:

PDF, 717 KB

2017

27

Synthesis of Bisected Glycoforms of Recombinant IFN-β by Overexpression of β-1,4-N-Acetylglucosaminyltransferase III in Chinese Hamster Ovary Cells

Adriana R. Sburlati, Pablo Umaña, Elisabetta G. P. Prati, James E. Bailey

Journal:

Biotechnology Progress

Year:

1998

Language:

english

File:

PDF, 74 KB

english, 1998

28

Identificación molecular y distribución potencial del anfípodo terrestre Talitroides topitotum (Crustacea:Amphipoda:Talitridae) en Costa Rica

Umaña-Castro, Rodolfo, Cambronero-Granados, José Antonio, Carvajal-Sánchez, José Pablo, Alfaro-Montoya, Jorge

Journal:

Acta Biológica Colombiana

Year:

2018

File:

PDF, 530 KB

2018

29

A small-scale method for the preparation of plant N-linked glycans from soluble proteins for analysis by MALDI-TOF mass spectrometry

Saskia R. Karg, Alexander D. Frey, Claudia Ferrara, Daniel K. Streich, Pablo Umaña, Pauli T. Kallio

Journal:

Plant Physiology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 292 KB

english, 2009

30

Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

Klein, Christian, Lammens, Alfred, Schäfer, Wolfgang, Georges, Guy, Schwaiger, Manfred, Mössner, Ekkehard, Hopfner, Karl-Peter, Umaña, Pablo, Niederfellner, Gerhard

Journal:

Year:

2013

Language:

english

File:

PDF, 2.91 MB

english, 2013

31

Comparison of the in vitro effects of the anti-CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells

Michaela Patz, Polina Isaeva, Nche Forcob, Bianka Müller, Lukas P. Frenzel, Clemens-Martin Wendtner, Christian Klein, Pablo Umana, Michael Hallek, Günter Krause

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 297 KB

english, 2011

32

A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

Herter, Sylvia, Morra, Laura, Schlenker, Ramona, Sulcova, Jitka, Fahrni, Linda, Waldhauer, Inja, Lehmann, Steffi, Reisländer, Timo, Agarkova, Irina, Kelm, Jens M., Klein, Christian, Umana, Pablo, Baca

Journal:

Cancer Immunology, Immunotherapy

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

33

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins

Jost, Christian, Darowski, Diana, Challier, John, Pulko, Vesna, Hanisch, Lydia J, Xu, Wei, MÃ¶ssner, Ekkehard, Bujotzek, Alexander, Klostermann, Stefan, Umana, Pablo, Kontermann, Roland E., Klein, Chr

Journal:

Year:

2020

File:

PDF, 2.36 MB

2020

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